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Subject: Peripheral Denervation in Cervical Dystonia (MovDis Congress 2000)

Date: 6/20/2000

E-MOVE reports from the 6th International Congress of Parkinson's Disease and Movement Disorders, held in Barcelona, Spain, 11-15 June 2000. Citation numbers refer to abstract numbers published in Movement Disorders 2000;15 (Supplement 3). 
 
1. Selective peripheral denervation for cervical dystonia: Selection criteria 
R Benabou, P Molina-Negro, G Bouvier 
P 738 
 
From experience with 450 cervical dystonia patients receiving selective peripheral denervation over 20 years, the authors propose the following selection criteria: 
--resistance to medical treatment, including BTX 
--stable clinical picture for at least 1, and preferably 3, years 
--dystonia restricted to or most pronounced in the cervical region 
 
They note that rotatory CD, either pure or combined with mild retro- or antecollis, shows the best post-operative outcome, while previous surgical operations, fibrosis, or arthritis reduce the likelihood of improvement. 
 
 
2. Prospective study of selective peripheral denervation for botulinum-toxin resistant patients with cervical dystonia 
A Munchau, JD Palmer, D Dressler, J O'Sullivan, KL Tsang, M Jahanshahi, N Quinn, AJ Lees, KP Bhatia 
P712 
 
Forty patients with BTX-resistant cervical dystonia received selective peripheral denervation. Mean follow-up of 9.4 months showed 60% of patients had significant functional improvement following surgery, with 25% reduction in TWSTRS score at 6 months and 1 year. At these two time points, severity subscore was reduced by 20% and 13% compared to baseline (p=0.01 for the difference ), disability subscore was reduced by 25% and 40% (p<0.0001), and pain subscore by 30% and 20% (n.s.). Six patients with primary BTX treatment failure obtained no benefit except 30% reduction of pain at 6 months. Mild-to-moderate dysphagia was reported in 12 patients, and persisted in 7. Severe dysphagia occurred in 2 patients, and persisted in 1. Swallowing improved in 4 patients.
E-MOVE Editor: Richard Robinson, NASW, WE MOVE
 
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